Irradiation of blood and blood components to prevent post-transfusion graft-versus-host disease in Japan

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Variation in blood component irradiation practice: implications for prevention of transfusion-associated graft-versus-host disease.

RAFT-VERSUS-HOST DISEASE (GVHD) is comG monly observed after allogeneic bone marrow transplantation (BMT), but transfusion-associated (TA) GVHD is only rarely reported. Although early reports of TAGVHD were recognized in immunocompromised hosts, more recent cases have been documented in immunocompetent transfusion recipients. The increasing awareness of this serious complication of transfusion ...

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Guidelines on gamma irradiation of blood components for the prevention of transfusion-associated graft-versus-host disease. BCSH Blood Transfusion Task Force.

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Fatal graft-versus-host disease following blood transfusion in Hodgkin's disease documented by HLA typing.

Fatal graft-versus-host disease (GVHD) developed in a patient with Hodgkin's disease treated with combined chemotherapy and radiotherapy following the transfusion of 2 U of packed red blood cells. Clinical features of the GVHD included the development of exfoliative dermatitis, progressive hepatic dysfunction, aplastic anemia, and finally progressive fatal pneumonia. GVHD was documented by skin...

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Transfusion Associated Graft versus Host Disease

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Transfusion-associated graft-versus-host disease

Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but almost uniformly lethal complication of blood transfusion. Although the graft-versus-host disease (GVHD) that occurs after allogeneic bone marrow transplantation and TA-GVHD share some clinical similarities, GVHD after bone marrow transplant is not uncommon and often responds positively to immunosuppression. The much rarer...

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ژورنال

عنوان ژورنال: Journal of the Japanese Society of Intensive Care Medicine

سال: 2012

ISSN: 1340-7988,1882-966X

DOI: 10.3918/jsicm.19.27